“I was just amazed that you could change what price you were going to launch a product at, and you could change what brand it was, and people would have dramatically different impressions of that product. And they would tell you incredibly different things about the product: they thought it was made of different materials, they thought it weighed more or it weighed less. Really out-there stuff that, at the time, we joked about but we couldn’t explain.”
More here. And meanwhile, for your listening pleasure …
Many people take glucosamine and chondroitin supplements for arthritis pain, but a controlled trial has found no evidence that the combination works. In fact, in this study, the placebo worked better.
Spanish researchers randomized 164 men and women with knee osteoarthritis to take a single daily dose of 1,500 milligrams of glucosamine and 1,200 of chondroitin, or an identical looking placebo. The study is in Arthritis & Rheumatology.
New research has shown that patient’s envisioning and expecting positive results from major surgery, including open heart surgery, will over time actually recover and heal more effectively.
“Optimizing patients’ expectations pre-surgery helps to improve outcome 6 months after treatment. This implies that making use of placebo mechanisms has the potential to improve long-term outcome of highly invasive medical interventions”
‘Cognitive enhancers’? Oh, do us a favour. Highly hyped and highly price energy drinks like Red Bull are all about the sugar and the caffeine, that’s all. Lots of sugar and caffeine. So why pay the premium, the enormous mark-up? It’s marketing, probably one of the shiniest examples of the placebo effect in marketing. Some science on this over here.
We note an interesting ‘counter narrative’ emerging – that is, scepticism about the commonly held view that drug treatments designed for mood disorders such as depression often engage the Placebo Effect. In this counter-narrative,
“Drug trials don’t show much in the way of classic placebo effects. The rise in placebo responses over the years is more likely due to the supportive factors in drug trials…and increasing problems with enrollment.”
The new finding—no upward trend in placebo responses—is unexpected and certain to be contested. Meanwhile, it stands as a rebuke to a popular narrative. By that account, drug effects had been hyped, expectations soared, and the inflated hopes were reflected in rising placebo response rates.”
This is fine, except the counter-narrative also resonates with challenges about the efficacy of conventional ‘gold-standard’ ‘blind’ ‘placebo controlled’ drug trials, where it has been shown that trials funded by drug companies (who by definition have a vested interest in their outcome) are 30% more likely to return ‘favourable’ results than trials which are not funded in this way. The ‘placebo effect’ might be the design and execution of the trial itself, not the actual function and efficacy of the placebo …!
‘VR Placebo interventions’ …! We do indeed live in a time of wonders. Research is being undertaken into the value of the emerging Virtual Reality technologies in treatment of mental illness. It’s early days, but the results so far are promising. Read more here.
‘There is now evidence showing some people, known as “placebo responders”, do feel or get better after unwittingly, or even wittingly, taking a placebo – and it’s not just psychosomatic. Several studies are pointing to a biological basis for the placebo effect, with the latest research focused on a region of the brain known as the mid-frontal gyrus, which runs along the frontal lobes just above the eyes.’